• Papers

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• [1] Mingxue Ma, Sai Shi, Zhifen Huang, Tingting Qi, Tianjie You, Ying Wang, Guzhen Zhang, Jiahui Liu, Jingyao Liu, Fenghui Guan*, Si Liu*, Sheng Ye*, Enhancing the Stability of Sweet Protein Neoculin for Food Applications Using Computational Strategies, Journal of Agricultural and Food Chemistry, 2025, 73(11): 6867–6877. (*equal corresponding)
• [2] Xiangyao Wang, Mengyu Zhang, Enli Zhang, Qiwei Wang, Yiqing Guo, Dingfan Xu, Congran Yue, Haozhe Cui, Zhiming Zhao*, Sheng Ye*, Si Liu*, Preparation of Multimeric peptide-MHC with SpyCatcher Modules for Antigen-Specific T Cell Detection, Sensors and Actuators: B. Chemical, 2025, 430(137342). (*equal corresponding)
• • [3] Qiwei Wang, Zhifen Huang, Sen Ma, Mingxue Ma, Sheng Ye*, Si Liu*, Engineering a cpGFP-Based Biosensor for Enhanced Quantification of Glycolate Production in Escherichia coli, Talanta, 2025, 286(127529). (*equal corresponding)
  • [4] Yiqing Guo, Yuxuan Bao, Zhichao Chen, Zhiheng Rao, Yongde Luo*, Sheng Ye*, Si Liu*, Novel FGF21 analogues through structure-based optimization for therapeutic development, Acta Biochimica et Biophysica Sinica, 2024, 2024, 57(4): 1–6. (*equal corresponding)
  • [5] Pei Zhu, Mingxue Ma, Tianjie You, Bo Zhang, Sheng Ye*, Si Liu*, Optimizing prolyl hydroxylation for functional recombinant collagen in Escherichia coli, International Journal of Biological Macromolecules, 2024, 282(137400). (*equal corresponding)
  • [6] Qiwei Wang, Sai Shi, Si Liu*, Sheng Ye*, A user-friendly fluorescent biosensor for precise lactate detection and quantification in vitro, ChemComm, 2024, 60, 12884-12887. (*equal corresponding)
  • [7] Mengyu Zhang, Xiangyao Wang, Junjie Wu, Qiwei Wang, Haozhe Cui, Xiaofeng Chen, Zhiming Zhao*, Si Liu*, Sheng Ye*, Preparation empty peptide-receptive MHC Class I complex for large-scale detection through photolabile peptide ligands, International Journal of Biological Macromolecules, 2024, 276(133781). (*equal corresponding)
  • [8] Pei Zhu; Tianjie You; Ying Wang; Mingxue Ma; Sheng Ye*; Si Liu*; A Cysteine-Maleimide-Based Design for Hemostatic, Antibacterial, and Biodegradable Wound Dressing, Bioconjugate Chemistry, 2024,35: 203−213. (*equal corresponding)
  • [9] Yanmei Liu; Jiayu Xu; Mingxue Ma; Tianjie You; Sheng Ye*; Si Liu*, Computational design towards a boiling-resistant single-chain sweet protein monellin, Food Chemistry, 2024, 440(138279). (*equal corresponding)
  • [10] Xie, Yuan, Chang Shenghai, Zhao Cheng; Wang Feng, Liu Si*, Wang Jin, Delpire Eric, Ye Sheng, Guo Jiangtao, Structures and an activation mechanism of human potassium-chloride cotransporters, Science Advances, 2020, 6(50): 0-eabc5883.
  • [11] Si Liu*, Shenghai Chang, Binming Han, Lingyi Xu, Mingfeng Zhang, Cheng Zhao, Wei Yang, Feng Wang, Jingyuan Li, Eric Delpire, Sheng Ye, Xiao-chen Bai, Jiangtao Guo, Cryo-EM structures of the human cation-chloride cotransporter KCC1, Science, 2019, 366:505–508.(*equal contribution)
  • [12] Si Liu*, Lingyi Xu, Fenghui Guan, Yun-Tao Liu, Yanxiang Cui, Qing Zhang, Xiang Zheng, Guo-Qiang Bi, Z. Hong Zhou, Xiaokang Zhang & Sheng Ye, Cryo-EM structure of the human α5β3 GABAA receptor. Cell Research, 2018, 28:958–961.(*equal contribution)
  • [13] Gu M, Liu Z, Lai R, Liu S*, Lin W, Ouyang C, Ye S, Huang H, Wang X, RKIP and TBK1 form a positive feedback loop to promote type I interferon production in innate immunity. EMBO J, 2016, 35(23):2553-2565.

• Honors & Awards
• [1] 天津大学2024届本科生毕业设计（论文）优秀指导教师