Zhang Pengfei
School
School of Precision Instrument and Optoelectronics Engineering
Professional Title
Associate professor
Discipline
光电子
Contact Information
pfzhang@tju.edu.cn
Brief Introduction
天津大学精密仪器与光电子工程学院，英才副教授，博士生导师。长期开展光谱学和光学检测与成像研究，研究兴趣主要包括光学压缩成像、拉曼光谱检测与成像、单细胞分析和操控、超声的全光学探测、光声成像等，在Optica, Light：Science & Applications, Nature Protocol, Photonics Research, Analytical Chemistry, Optics Letters, Optics Express等国际权威期刊上发表论文50余篇，论文被引用2000多次，h-index 27。担任Advanced Science, Optica, ACS photonics, Photonics Research, Optics Letters, Optics Express等学术期刊审稿人。
Education Background
- Bachelor’s Degree| Northwestern Polytechnical University| Applied Physics| 2002
- Doctoral degree| Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences| Optics| 2008
Research Interests
- Raman spectroscopy and imaging; Single cell analysis; Photoacoustic imaging; Optical manipulation
Positions & Employments
-
2018.5-Now
精密仪器与光电子工程学院 | 天津大学 | 副教授 -
2016.1-2017.1
Washington University in St. Louis | Research Associate -
2012.6-2015.6
Los Alamos National Laboratory | Postdotoral Research Associate -
2009.2-2011.12
East Carolina University | Postdoc -
2008.7-2009.1
上海广电光电子技术有限公司 | 研发工程师
Academic Achievements
- Papers
- [1] Pengfei Zhang*, Yuhan Miao, Yiwen Ma, Pengfei Niu, Liang Zhang, Limin Zhang, and Feng Gao. All-optical ultrasonic detector based on differential interference. Optics Letters, 47(18), 4790-4793 (2022).
- [2] Hang Yuan, Pengfei Zhang*, Feng Gao, and Xianyu Bao, Combination of scattering-projection interleaving and random down-sampling for compressive confocal Raman imaging.Optics Express, 30(25), 44657-44664 (2022)
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- [3] Zhenzhen Li, Xiujuan Zhang, Chengui Xiao, Da Chen, Shushi Huang, Pengfei Zhang*, Guiwen Wang*. Combination of multi-focus Raman spectroscopy and compressive sensing for parallel monitoring of single-cell dynamics. Journal of Innovative Optical Health Sciences, 14(6): 2150021 (2021).
- [4] Hang Yuan, Pengfei Zhang*, and Feng Gao, “Compressive hyperspectral Raman imaging via randomly interleaved scattering projection”, Optica 8, 1462-1470 (2021).
- [5] P Zhang*, G Wang*, S Huang, “Parallel micro-Raman spectroscopy of multiple cells in a single acquisition using hierarchical sparsity”, Analyst, 145, 6032-6037 (2020).
- [6] Zhang P.*, Wang, G., Zhang, X., Li, Y.-Q*, “Single-acquisition 2-D multifocal Raman spectroscopy using compressive sensing,” Analytical Chemistry, 92 (1), 1326-1332 (2020).
- [7] D Chen, T Wang, Y Ma, G Wang, Q Kong, P Zhang*, R Li*, Rapid characterization of heavy metals in single microplastics by laser induced breakdown spectroscopy, Science of The Total Environment, 743, 140850 (2020).
- [8] Chen, D., Huang, Z., Wang, T., Ma, Y., Zhang, Y., Wang, G., Zhang, P.*, “High-throughput analysis of single particles by micro laser induced breakdown spectroscopy,” Analytica Chimica Acta, 1095, 14-19 (2020).
- [9] Zhang P., Huang, Z., Ma, Y., Li, Y., Ali, N., Li, Q., Chen, D., “On-line detection of radioactive and non-radioactive heavy metals in tobacco smoke using portable laser-induced breakdown spectroscopy,” Analyst, 144, 3567-3572 (2019).
- [10] Miao, Z., Zhang P., Zhang Y., Huang X., Liu J., Wang G., “Single-cell analysis reveals the effects of glutaraldehyde and formaldehyde on individual Nosema bombycis spores.”, Analyst, 144 (9), 3136-3143 (2019).
- [11] Zhang, P., Li, L., Lin, L., Shi, J., and Wang, L. V., “In vivo superresolution photoacoustic computed tomography by localization of single dyed droplets,”. Light: Science & Applications, 8(1), 36 (2019).
- [12] Micheva-Viteva, S. N., Ross, B. N., Gao, J., Adikari, S., Zhang, P., Mourant, J. R., & Hong-Geller, E., “Increased mortality in mice following immunoprophylaxis therapy with high dosage of nicotinamide in Burkholderia persistent infections,” Infection and immunity, 87(1), e00592-18 (2019).
- [13] Zhang, P. *, Song, G., and Yu, L., "Optical Trapping of Single Quantum Dots for Cavity Quantum Electrodynamics," Photonics Research, 6(3): 182-185 (2018).
- [14] Rao, L., Feeherry, F., Ghosh, S., Liao, X., Lin, X., Zhang, P., Li, Y., Doona, C., and Setlow, P., "Effects of lowering water activity by various humectants on germination of spores of Bacillus species with different germinants," Food Microbiology, 72, 112-127 (2018).
- [15] Fu, H., Li, S., Wang, Y., Song, G., Zhang, P., Wang, L., Yu, L., "Independently Tunable Ultrasharp Double Fano Resonances in Coupled Plasmonic Resonator System," IEEE Photonics Journal, 10(1), 4800409 (2018).
- [16] Zhang, P., Li, L., Lin, L., Hu, P., Shi, J., He, Y., Zhu, L., Zhou, Y., and Wang, L.V., "High-resolution deep functional imaging of the whole mouse brain by photoacoustic computed tomography in vivo," Journal of Biophotonics, 11(1): e201700024 (2018).
- [17] Lin, L.†, Zhang, P. †, Xu, S., Shi, J., Li, L., Yao, J., Wang, L., and Wang, L.V., "Hand-held optical-resolution photoacoustic microscopy," Journal of Biomedical Optics, 22(4), 041002(2017).
- [18] Zhang, P., Goodwin, P.M., and Werner, J.H., "Light-sheet Microscopy by confocal line scanning of dual-Bessel Beams," Journal of Biomedical Optics, 21 (10), 100502 (2016).
- [19] Tao, Z., Zhang, P., Qin, Z., Li, Y.Q. and Wang, G., "Poly(3-hydroxybutyrate) anabolism in Cupriavidus necator cultivated at various carbon-to-nitrogen ratios: insights from single-cell Raman spectroscopy," Journal of Biomedical Optics, 21(9), 097005-097005 (2016).
- [20] Tao, Z., Peng, L., Zhang, P., Li, Y.Q. and Wang, G., "Probing the Kinetic Anabolism of Poly-Beta-Hydroxybutyrate in Cupriavidus necator H16 Using Single-Cell Raman Spectroscopy," Sensors, 16(8), 1257 (2016).
- [21] Liang, J., Zhang, P., Setlow, P., and Li, Y.-Q., "High-precision fitting measurements of the kinetics of size changes during germination of individual Bacillus spores," Applied and Environmental Microbiology, 80(15), 4606-4615 (2014).
- [22] Zhang, P., Goodwin, P.M., and Werner, J.H., "Fast, super resolution imaging via Bessel-beam stimulated emission depletion microscopy," Optics Express, 22, 12398-12409 (2014).
- [23] Zhang, P., Phipps, M.E., Goodwin, P.M., and Werner, J.H., "Confocal line scanning of a Bessel beam for fast 3D Imaging," Optics Letters, 39(12), 3682-3685 (2014).
- [24] Zhang, P., Goodwin, P.M., and Werner, J.H., “Interferometric three-dimensional single molecule localization microscopy using a single high numerical-aperture objective,” Applied Optics, 53(31), 7415-7421 (2014).
- [25] Zhang, P., Liang, J., Yi, X., Setlow, P., and Li, Y.-Q., "Monitoring of Commitment, Blocking and Continuation of Nutrient Germination of Individual Bacillus subtilis Spores," Journal of Bacteriology, 196(13), 2443-2454 (2014).
- [26] Setlow, B., Parish, S., Zhang, P., Li, Y.-Q., Neely, C., and Setlow, P., "Mechanism of killing of spores of Bacillus anthracis in a high-temperature gas environment, and analysis of DNA damage generated by various decontamination treatments of spores of Bacillus anthracis," Journal of Applied Microbiology, 116, 805-814 (2014).
- [27] Ramirez-Peralta A., Zhang P., Li, Y.-Q., and Setlow, P., "Effects of Sporulation Conditions on the Germination and Germination Protein Levels of Spores of Bacillus subtilis," Applied and Environmental Microbiology, 78, 2689-2697 (2012).
- [28] Li, Y., Davis, A., Korza G., Zhang P., Li, Y.-Q., Setlow, B., Setlow, P., and Hao B., "Role of a SpoVA protein in dipicolinic acid uptake into developing spores of Bacillus subtilis," Journal of Bacteriology, 194(8), 1875-1884 (2012).
- [29] Zhang, P., Kong, L., Wang, G., Scotland, M., Ghosh S., Setlow, B., Setlow, P., and Li, Y.-Q., "Analysis of the slow germination of multiple individual superdormant B. subtilis spores using multifocus Raman microspectroscopy and DIC microscopy," Journal of Applied Microbiology, 112, 526-536 (2012).
- [30] Zhang, P., Thomas, S., Li, Y.-Q., and Setlow, P., "Effects of Cortex Peptidoglycan Structure and Cortex Hydrolysis on the Kinetics of Ca2+-Dipicolinic Acid Release During Bacillus subtilis Spore Germination," Journal of Bacteriology, 194, 646-652 (2012).
- [31] Kong L., Zhang P., Wang, G., Yu, J., Setlow, P., and Li, Y.-Q., "Characterization of bacterial spore germination using phase-contrast and fluorescence microscopy, Raman spectroscopy and optical tweezers," Nature Protocols, 6, 625–639 (2011).
- [32] Wang, G., Zhang, P., Setlow, P., and Li, Y.-Q., "Kinetics of germination of wet-heat-treated individual spores of Bacillus species, monitored by Raman spectroscopy and differential interference contrast microscopy," Applied and Environmental Microbiology, 77, 3368-3379 (2011).
- [33] Kong, L., Zhang, P., Yu, J., Setlow, P., and Li, Y.-Q., "Rapid confocal Raman imaging using a synchro multifoci-scan scheme for dynamic monitoring of single living cells," Applied Physics Letters, 98, 213703 (2011).
- [34] Zhang P., Kong, L., Wang, G., Setlow, P., and Li, Y.-Q., "Monitoring the wet-heat inactivation dynamics of single spores of Bacillus species by using Raman tweezers, differential interference contrast microscopy, and nucleic acid dye fluorescence microscopy," Applied and Environmental Microbiology, 77, 4754-4769 (2011).
- [35] Ghosh, S., Ramirez-Peralta, A., Gaidamakova, E., Zhang, P., Li, Y.-Q., Daly, M.J. and Setlow, P., "Effects of Mn levels on resistance of Bacillus megaterium spores to heat, radiation and hydrogen peroxide," Journal of Applied Microbiology, 111, 663–670 (2011).
- [36] Sanchez-Salas, J.-L., Setlow, B., Zhang, P., Li, Y.-Q., and Setlow, P., "Maturation of released spores is necessary for acquisition of full spore heat resistance during Bacillus subtilis sporulation," Applied and Environmental Microbiology, 77, 6746-6754 (2011).
- [37] Wang, G., Zhang, P., Paredes-Sabja, D., Green, C., Setlow, P., Sarker, M.R. and Li, Y.-Q., "Analysis of the germination of individual Clostridium perfringens spores and its heterogeneity," Journal of Applied Microbiology, 111, 1212–1223 (2011).
- [38] Kong, L., Zhang P., Setlow, P., and Li, Y.-Q., "Multifocus confocal Raman microspectroscopy for rapid single-particle analysis," Journal of Biomedical Optics, 16, 120503 (2011).
- [39] Zhang, P., Kong, L., Setlow, P., and Li, Y.-Q., "Multiple-trap laser tweezers Raman spectroscopy for simultaneous monitoring of the biological dynamics of multiple individual cells," Optics Letters, 35, 3321-3323 (2010).
- [40] Zhang, P., Garner, W., Yi, X., Yu, J., Li, Y.-Q., and Setlow, P., "Factors affecting variability in time between addition of nutrient germinants and rapid dipicolinic acid release during germination of spores of Bacillus species," Journal of Bacteriology, 192, 3608-3619 (2010).
- [41] Zhang, P., Kong, L., Setlow, P., and Li, Y.-Q., "Characterization of wet-heat inactivation of single spores of Bacillus species by dual-trap Raman spectroscopy and elastic light scattering," Applied and Environmental Microbiology, 76, 1796–1805 (2010).
- [42] Zhang, P., Kong, L., Wang, G., Setlow, P., and Li, Y.-Q., "Combination of Raman tweezers and quantitative differential interference contrast microscopy for measurement of dynamics and heterogeneity during the germination of individual bacterial spores," Journal of Biomedical Optics, 15, 056010 (2010).
- [43] Coleman, W.H., Zhang, P., Li, Y.-Q., and Setlow, P., "Mechanism of killing of spores of Bacillus cereus and Bacillus megaterium by wet heat," Letters in Applied Microbiology, 50, 507-514 (2010).
- [44] Kong, L., Zhang, P., Yu, J., Setlow, P., and Li, Y.-Q., "Monitoring the kinetics of uptake of a nucleic acid dye during the germination of single spores of Bacillus species," Analytical Chemistry, 82, 8717–8724 (2010).
- [45] Kong, L., Zhang, P., Setlow, P., and Li, Y.-Q., "Characterization of bacterial spore germination using integrated phase contrast microscopy, Raman spectroscopy, and optical tweezers," Analytical Chemistry, 82, 3840–3847 (2010).
- [46] Zhang, H., Zhang, P., Xu, X. Cheng, F., and Wang, Y., "Optimized temperature measurement with time-of-flight method", Optics Communications, 282, 3278-3281 (2009).
- [47] Ghosh, S., Zhang, P., Li, Y.-Q., and Setlow, P., "Superdormant spores of Bacillus species have elevated wet-heat resistance and temperature requirements for heat activation", Journal of Bacteriology, 191, 5584-5591 (2009).
- [48] Zhang, P., Setlow, P., and Li, Y.-Q., "Characterization of single heat-activated Bacillus spores using laser tweezers Raman spectroscopy," Optics Express, 17, 16480-16491 (2009).
- [49] Zhang, P., Zhang, H., Xu, X., and Wang, Y., "Cooling induced by parametric resonance in a magnetic quadrupole trap", Chinese Optics Letters, 6, 87-89 (2008).
- [50] Zhang, P., Zhang, H., Xu, X., and Wang, Y., "Monte Carlo simulation of cooling induced by parametric resonance," Chinese Physics Letters, 25, 89-92(2008).
- [51] 张鹏飞，许忻平，张海潮，周善钰，王育竹，"紫外光诱导原子脱附技术在单腔磁阱装载中的应用, "物理学报, 56 (6), 3205-3211 (2007).
- [52] Zhang H., Zhang P., Xu X., Han J., and Wang Y., "Trapping of neutral atoms with a radio-frequency field ", Chinese Physics Letters, 22 (1), 83-86(2005).
Team
生物医学光子成像研究室
- Honors & Awards