龚俊波
- 教师名称：龚俊波
- 教师拼音名称：Gong Junbo
- 出生日期：1974-03-20
- 性别：男
- 职务：Vice Director of NERCICT
- 学科：Industrial Crystallization
- 职称：教授
其他联系方式
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基本信息
研究方向
获奖情况
论文成果
- Prof. Gong has many years of experience in the research area of industrial crystallization, pharmaceutical and crystal engineering. He was an undergraduate student at Tianjin University(1991-1995), and got his Ph.D. degree from Department of Chemistry Engineering at Tianjin University(2001). Currently he is the vice director of the National Engineering Re...
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- Functional crystals (covalent organic frameworks, metal orgaic frameworks, optical crystals, elastic crystals, etc.)
- Continuous crystallization (software development, process simulation, equipment design, product optimization, etc.)
- Spherical crystallization (agglomeration-crushing mechanism, caking behavior, etc.)
- Crystal engineering (design and screening of pharmaceutical polymorphism, co-crystals, solvates, amorphous forms, salts, MOF, COF, etc.),
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- Hou debang chemical technology innovation award (2018)
- Chinese Patent Award of Excellence (2017)
- Grand prize of the Scientific and Technological Progress Award of Tianjin (2019)
- Chinese Patent Gold Medal (2019)
- Qinghai province high-end introduction of leading talent (2017)
- Youth Science and Technology Outstanding Contribution Award of CPCIF (2017)
- Young and middle-aged leading talents in science and technology innovation of the ministry of science and technology (2018)
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- Mingyang Chen, Xinyu Liu, Changyou Yu, Menghui Yao, ShijieXu, Weiwei Tang, Xiaopeng Song, Weibing Dong, Gang Wang, Junbo Gong*. Strategy of selecting solvent systems for spherical agglomeration by theLifshitz-van der Waals acid-base approach [J]. Chemical Engineering Science, 220: 115613 (2020).
- Yifu Chen, Bo Yu, Shijie Xu, Fuyan Ma, Junbo Gong*. Core–Shell-Structured Cyclodextrin Metal–Organic Frameworks for Programmable Cargo Release[J]. ACS applied materials & interfaces, 11(18): 16280-16284 (2019).
- Dandan Han, Tarak Karmakar, Zoran Bjelobrk, Junbo Gong*, Michele Parrinello*. Solvent-mediated morphology selection of the active pharmaceutical ingredient isoniazid: Experimental and simulation studies[J]. Chemical Engineering Science, 204: 320-328 (2019).
- Lina Jia, Songgu Wu, Junbo Gong*. A tolbutamide–metformin salt based on antidiabetic drug combinations: synthesis, crystal structure analysis and pharmaceutical properties[J]. Acta Crystallographica Section C: Structural Chemistry, 75(9): 1250-1258 (2019).
- Yifu Chen, Bo Yu, Yingdan Cui, Shijie Xu, Junbo Gong*. Core–Shell Structured Cyclodextrin Metal–Organic Frameworks with Hierarchical Dye Encapsulation for Tunable Light Emission[J]. Chemistry of Materials, 31(4): 1289-1295 (2019).
- Haiyan Yang, Yang Yang, Lina Jia, Weiwei Tang, Shijie Xu, Shichao Du, Mingchen Li, Junbo Gong*. The Phase Transformation and Formation Mechanism of Isostructural Solvates: A Case Study of Azoxystrobin[J]. Crystal Growth & Design, 19(3): 1550-1558 (2019).
- Si Li, Weiwei Tang, Mengya Li, Lingyu Wang, Yang Yang, Junbo Gong*. Understanding the Role of Citric Acid on the Crystallization Pathways of Calcium Oxalate Hydrates[J]. Crystal Growth & Design, 19(6): 3139-3147 (2019).
- Lingyu Wang, Weiwei Tang, Shichao Du, Shijie Xu, Peng Shi, Songgu Wu, Junbo Gong*. Surprising Effect of Carbon Chain Length on Inducing Ability of Additives: Elusive Form- II of γ-Aminobutyric Acid (GABA) Induced by Sodium Carboxylate Additives[J]. Crystal Growth & Design, 19(7): 3825-3833 (2019).
- Shiyuan Liu, Lina Jia, Shijie Xu, Yifu Chen, Weiwei Tang, Junbo Gong*. Insight into the State Evolution of Norfloxacin as a Function of Drug Concentration in Norfloxacin-PVP/HPMC/HPMCP Solid Dispersions[J]. Crystal Growth & Design, 19(11): 6239-6251 (2019).
- Dejiang Zhang, Xinyi Wang, Joachim Ulrich, Weiwei Tang, Shijie Xu, Zhonghua Li, Sohrab Rohani*, Junbo Gong*. Control of Crystal Properties in a Mixed-Suspension Mixed-Product Removal Crystallizer: General Methods and the Effects of Secondary Nucleation[J]. Crystal Growth & Design, 19(5): 3070-3084 (2019).
- Zhenguo Gao, Yuanyi Wu, Junbo Gong, Jingkang Wang, Sohrab Rohani*. Continuous crystallization of α-form L-glutamic acid in an MSMPR-Tubular crystallizer system[J]. Journal of Crystal Growth, 507: 344-351 (2019).
- Teng Zhang, Botond Szilágyi, Junbo Gong, Zoltan K. Nagy*. Thermodynamic polymorph selection in enantiotropic systems using supersaturation-controlled batch and semi-batch cooling crystallization[J]. Crystal Growth & Design, 19(11): 6715-6726 (2019).
- Shaolei Zhao, Jie Gao, Siyang Ma, Chao Li, Yiming Ma, Yang He, Junbo Gong, Fu Zhou, Bingyuan Zhang, Weiwei Tang*. Mechanism and Modelling of Reactive Crystallization Process of Lithium Carbonate[J]. Processes, 7(5): 248 (2019).
- Estevao G. J. Macaringue, Songgu Wu, Shiyuan Liu, Shijie Xu, Junbo Gong*. Influence of the Solvent Content on the Phase Transformation of Sulfadiazine N‐Methyl Pyrrolidone Solvate[J]. Chemical Engineering & Technology, 42(7): 1435-1445 (2019).
- Xinyi Wang, Yifu Chen, Junbo Gong*, Jinze Hou. Aggregation-induced emission and polymorphism/shape/size-dependent emission behaviours of fenamates for potential drug evaluation[J]. Organic & biomolecular chemistry, 17(13): 3409-3415 (2019).
- Ning Wei, Lina Jia, Zeren Shang, Junbo Gong, Songgu Wu, Jingkang Wang, Weiwei Tang*. Polymorphism of levofloxacin: structure, properties and phase transformation[J]. CrystEngComm, 21, 6196-6207 (2019).
- Xinyi Wang, Shijie Xu, Lina Jia, Yujia Yang, Yu Liu, Junbo Gong, Songgu Wu*. Drug–drug salts of mefenamic acid olfenamic acid and piperazine to improve physicochemical properties for potential veterinary use[J]. CrystEngComm, 21(35): 5284-5291 (2019).
- Yufeng Quan, Yang Yang, Shijie Xu, Peipei Zhu, Shiyuan Liu, Lina Jia, Junbo Gong*. Insight into the role of piperazine in the thermodynamics and nucleation kinetics of the triethylenediamine–methyl tertiary butyl ether system[J]. CrystEngComm, 21(6): 948-956 (2019).
- Yu Liu, Lina Jia, Songgu Wu, Shijie Xu, Xu Zhang, Shuang Jiang, Junbo Gong*. Polymorphism and molecular conformations of nicosulfuron: structure, properties and desolvation process[J]. CrystEngComm, 21(17): 2790-2798 (2019).
- Zhonghua Li, Lina Jia, Peng Shi, Shuang Jiang, Junbo Gong, Songgu Wu*. Versatile solid forms of boscalid: insight into the crystal structures and phase transformations[J]. CrystEngComm, 21, 6838-6849 (2019).
- Zhonghua Li, Peng Shi, Yang Yang, Panpan Sun, Yan Wang, Shijie Xu, Junbo Gong*. Tuning crystallization and stability of the metastable polymorph of dl-methionine by a structurally similar additive[J]. CrystEngComm, 21, 3731-3739 (2019).
- Lina Jia, Yang Yu, Mengwei Wang, Hanzhi, Junbo Gong*. Preparation and characterization for multicomponent crystals of the antidiabetic drug gliquidone based on crystal engineering[J]. CrystEngComm, 21(10): 1617-1625 (2019).
- Dandan Han, Yan Wang, Yang Yang, Tingting Gong, Yifu Chen, Junbo Gong*. Revealing the role of a surfactant in the nucleation and crystal growth of thiamine nitrate: experiments and simulation studies[J]. CrystEngComm, 21, 3576-3585 (2019).
- Yan Wang, Shichao Du, Xuemei Wang, Mengmeng Sun, Yujia Yang, Junbo Gong*. Spherulitic growth and morphology control of lithium carbonate: the stepwise evolution of core-shell structures[J]. Powder Technology, 355: 617-628 (2019).
- Zhenguo Gao, Yuanyi Wu, Junbo Gong, Jingkang Wang, Sohrab Rohani*. Continuous crystallization of α-form L-glutamic acid in an MSMPR-Tubular crystallizer system[J]. Journal of Crystal Growth, 507: 344-351 (2019).
- Teng Zhang, Botond Szilágyi, Junbo Gong, Zoltan K. Nagy*. Thermodynamic polymorph selection in enantiotropic systems using supersaturation-controlled batch and semi-batch cooling crystallization[J]. Crystal Growth & Design, 19(11): 6715-6726 (2019).
- Shaolei Zhao, Jie Gao, Siyang Ma, Chao Li, Yiming Ma, Yang He, Junbo Gong, Fu Zhou, Bingyuan Zhang, Weiwei Tang*. Mechanism and Modelling of Reactive Crystallization Process of Lithium Carbonate[J]. Processes, 7(5): 248 (2019).
- Estevao G. J. Macaringue, Songgu Wu, Shiyuan Liu, Shijie Xu, Junbo Gong*. Influence of the Solvent Content on the Phase Transformation of Sulfadiazine N‐Methyl Pyrrolidone Solvate[J]. Chemical Engineering & Technology, 42(7): 1435-1445 (2019).
- Xinyi Wang, Yifu Chen, Junbo Gong*, Jinze Hou. Aggregation-induced emission and polymorphism/shape/size-dependent emission behaviours of fenamates for potential drug evaluation[J]. Organic & biomolecular chemistry, 17(13): 3409-3415 (2019).
- Ning Wei, Lina Jia, Zeren Shang, Junbo Gong, Songgu Wu, Jingkang Wang, Weiwei Tang*. Polymorphism of levofloxacin: structure, properties and phase transformation[J]. CrystEngComm, 21, 6196-6207 (2019).
- Xinyi Wang, Shijie Xu, Lina Jia, Yujia Yang, Yu Liu, Junbo Gong, Songgu Wu*. Drug–drug salts of mefenamic acid olfenamic acid and piperazine to improve physicochemical properties for potential veterinary use[J]. CrystEngComm, 21(35): 5284-5291 (2019).
- Yufeng Quan, Yang Yang, Shijie Xu, Peipei Zhu, Shiyuan Liu, Lina Jia, Junbo Gong*. Insight into the role of piperazine in the thermodynamics and nucleation kinetics of the triethylenediamine–methyl tertiary butyl ether system[J]. CrystEngComm, 21(6): 948-956 (2019).
- Yu Liu, Lina Jia, Songgu Wu, Shijie Xu, Xu Zhang, Shuang Jiang, Junbo Gong*. Polymorphism and molecular conformations of nicosulfuron: structure, properties and desolvation process[J]. CrystEngComm, 21(17): 2790-2798 (2019).
- Zhonghua Li, Lina Jia, Peng Shi, Shuang Jiang, Junbo Gong, Songgu Wu*. Versatile solid forms of boscalid: insight into the crystal structures and phase transformations[J]. CrystEngComm, 21, 6838-6849 (2019).
- Zhenguo Gao, Yang Wu, Yuanyi Wu, Junbo Gong, Ying Bao, Jingkang Wang, Sohrab Rohani*. Self-Induced Nucleation During the Antisolvent Crystallization Process of Candesartan Cilexetil[J]. Crystal Growth & Design, 18(12): 7655-7662 (2018).
- Ergang Liu, Meng Zhang, Hui Cui, Junbo Gong, Yongzhuo Huang, Jianxin Wang, Yanna Cui, Weibing Dong, Lu Sun, Huining He*, Victor C. Yang*. Tat-functionalized Ag-Fe3O4 nano-composites as tissue-penetrating vehicles for tumor magnetic targeting and drug delivery[J]. Acta pharmaceutica sinica B, 8(6): 956-968 (2018).
- Zhenguo Gao, Yuanyi Wu, Ying Bao, Junbo Gong, Jingkang Wang, Sohrab Rohani*. Image Analysis for In-line Measurement of Multidimensional Size, Shape, and Polymorphic Transformation of l-Glutamic Acid Using Deep Learning-Based Image Segmentation and Classification[J]. Crystal Growth & Design, 18(8): 4275-4281 (2018).
- Yanan Wu, Ling Zhou, Xia Zhang, Junbo Gong, Hongxun Hao, Qiuxiang Yin*, Zhao Wang*. Determination and Correlation of the Solubility of Acetylpyrazine in Pure Solvents and Binary Solvent Mixtures[J]. Journal of Solution Chemistry, 47(5): 950-973 (2018).
- Zhenguo Gao, Fatima Altimimi, Junbo Gong, Ying Bao*, Jingkang Wang, Sohrab Rohani*. Ultrasonic irradiation and seeding to prevent metastable liquid–liquid phase separation and intensify crystallization[J]. Crystal Growth & Design, 18(4): 2628-2635 (2018).
- Mengmeng Sun, Shichao Du, Mingyang Chen, Sohrab Rohani§Huihui Zhang, Ya Liu, PanPan Sun, Yaping Wang, Peng Shi, Shijie Xu, Junbo Gong*. Oiling-out investigation and morphology control of β-alanine based on ternary phase diagrams[J]. Crystal Growth & Design, 18(2): 818-826 (2018).
- Dandan Han, Bo Yu, Yumin Liu, Shichao Du, Sohrab Rohani, Teng Zhang, Shiyuan Liu, Peng Shi, Haisheng Wang, Lina Zhou, Junbo Gong*. Effects of Additives on the Morphology of Thiamine Nitrate: The Great Difference of Two Kinds of Similar Additives[J]. Crystal Growth & Design, 18(2): 775-785 (2018).
- Shijie Xu, Yifu Chen, Junbo Gong*. Jingkang Wang, Interplay between Kinetics and Thermodynamics on the Probability Nucleation Rate of a Urea–Water Crystallization System[J]. Crystal Growth & Design, 18(4): 2305-2315 (2018).
- Shasha Jin, Mingyang Chen, Zhenfang Li, Songgu Wu, Shichao Du, Shijie Xu, Sohrab Rohani, Junbo Gong*. Design and mechanism of the formation of spherical KCl particles using cooling crystallization without additives[J]. Powder Technology, 329: 455-462 (2018).
- Xiaoyan Fu, Dejiang Zhang, Shijie Xu, Bo Yu, Keke Zhang, Sohrab Rohani, Junbo Gong*. Effect of Mixing on the Particle Size Distribution of Paracetamol Continuous Cooling Crystallization Products Using a Computational Fluid Dynamics–Population Balance Equation Simulation[J]. Crystal Growth & Design, 18(5): 2851-2863 (2018).
- Keke Zhang, Shijie Xu, Shiyuan Liu, Weiwei Tang, Xiaoyan Fu, Junbo Gong*. Novel Strategy to Control Polymorph Nucleation of Gamma Pyrazinamide by Preferred Intermolecular Interactions during Heterogeneous Nucleation[J]. Crystal Growth & Design, 18(9): 4874-4879 (2018).
- Mingyang Chen, Songgu Wu, Shijie Xu, Bo Yu, Mohannad Shilbayeh, Ya Liu, Xiaowen Zhu, Jingkang Wang, Junbo Gong*. Caking of crystals: Characterization, mechanisms and prevention[J]. Powder Technology, 337: 51-67 (2018).
- Peng Shi, Shijie Xu, Shichao Du, Sohrab Rohani, Shiyuan Liu, Weiwei Tang, Lina Jia, Jingkang Wang, Junbo Gong*. Insight into Solvent-Dependent Conformational Polymorph Selectivity: The Case of Undecanedioic Acid[J]. Crystal Growth & Design,18(10): 5947-5956 (2018).
- Shiyuan Liu, Shijie Xu, Weiwei Tang, Bo Yu, Baohong Hou, Junbo Gong*. Revealing the roles of solvation in D-mannitol's polymorphic nucleation[J]. CrystEngComm, 20(46): 7435-7445 (2018).
- Weiwei Tang, Mingtao Zhang, Huaping Mo, Junbo Gong*, Jingkang Wang, Tonglei Li. Higher-order self-assembly of benzoic acid in solution[J]. Crystal Growth & Design, 17: 5049-5053 (2017).
- Weiwei Tang, Huaping Mo, Mingtao Zhang, Junbo Gong*, Jingkang Wang, Tonglei Li. Glycine’s pH-Dependent Polymorphism: A Perspective from Self-Association in Solution[J]. Crystal Growth & Design, 17: 5028-5033 (2017).
- Teng Zhang, Yumin Liu, Shichao Du, Songgu Wu, Dandan Han, Shiyuan Liu, Junbo Gong*. Polymorph control by investigating the effects of solvent and supersaturation on clopidogrel hydrogen sulfate in reactive crystallization[J]. Crystal Growth & Design, 17: 6123-6131 (2017).
- Panpan Sun, Yaping Wang, Sohrab Rohani, Ergang Liu, Shichao Du, Shijie Xu, Mingyang Chen, Zhenping Wei, Junbo Gong*. Controlled Recrystallization of Tubular Vinpocetine Crystals with Increased Aqueous Dissolution Rate and In Vivo Bioavailability[J]. Crystal Growth & Design, 17: 5790-5800 (2017).
- Weiwei Tang, Huaping Mo, Mingtao Zhang, Sean Parkin, Junbo Gong*, Jingkang Wang, Tonglei Li, Persistent self-association of solute molecules in solution[J]. The Journal of Physical Chemistry B, 121: 10118-10124 (2017).
- Bo Yu, Jie Hou, Junbo Gong*. Amorphous Co (MeIm) 2 framework coating on AuCo for size-selective photocatalysis and interface transfer[J]. Catalysis Science & Technology, 7: 5004-5010 (2017).
- Jie Hou, Chunlei Guo, Yuzhi Shi, Ergang Liu, Weibing Dong, Bo Yu, Shiyuan Liu, Junbo Gong*. A novel high drug loading mussel-inspired polydopamine hybrid nanoparticle as a pH-sensitive vehicle for drug delivery[J]. International journal of pharmaceutics, 533: 73-83 (2017).
- Shichao Du, Yan Wang, Songgu Wu, Bo Yu, Peng Shi, Lin Bian, Dejiang Zhang, Jie Hou, Jingkang Wang, Junbo Gong*. Two novel cocrystals of lamotrigine with isomeric bipyridines and in situ monitoring of the cocrystallization[J]. European Journal of Pharmaceutical Sciences, 110: 19-25 (2017).
- Zhilong Luo, Yingdan Cui, Weibing Dong, Qipeng Xu, Gaoxing Zou, Chao Kang, Baohong Hou, Song Chen, Junbo Gong*. Morphological diversity of nitroguanidine crystals with enhanced mechanical performance and thermodynamic stability[J]. Journal of Crystal Growth, 480: 132-140 (2017).
- Lina Jia, Shijie Xu, Shiyuan Liu, Shichao Du, Songgu Wu, Junbo Gong*. Polymorphs of daidzein and intermolecular interaction effect on solution crystallization[J]. CrystEngComm, 19: 7146-7153 (2017)
- Dejiang Zhang, Shijie Xu, Shichao Du, Jingkang Wang, Junbo Gong*. Progress of pharmaceutical continuous crystallization[J]. Engineering, 3: 354-364 (2017).
- 1、 Songgu Wu, Junbo Gong*, etc. Solvent penetration mediated phase transformation for the preparation of aggregated particles with well-defined shape. Cryst EngComm. 18(48): 9223-9226 (2016).2019
- 15、 Weiwei Tang, Junbo Gong*, etc. Solubility of androstenedione in lower alcohols. Fluid Phase Equilibrium. 363:86– 96 (2014) .2019
- 2、 Shijie Xu, Junbo Gong*, etc. Nucleation behavior of eszopiclone-butyl acetate solutions from metastable zone widths. Chemical Engineering Science. , 155: 248-257 (2016).2019
- 14、 Wei Du, Junbo Gong*, etc. Solution-mediated polymorphic transformation of prasugrel hydrochloride from form II to form I. Industrial & Engineering Chemistry Research. 53(14): 5652-5659 (2014) .2019
- 3、 Bo yu, Junbo Gong*, etc. Phase Transfer Directed Synthesis of Hollow Zeolitic Imidazolate Frameworks-67 Nanocages. Crystal Growth & Design. 17(1)：3-6 (2017).2019
- 6、 Ze Liu, Junbo Gong, etc. Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment. Nature communications. 5: 4280 (2014).2019
- 7、 Wei Du, Junbo Gong*, etc. Concomitant Polymorphism of Prasugrel Hydrochloride in Reactive Crystallization. Industrial and Engineering Chemistry Research. 52(46): 16182-16189 (2013).2019
- 8、 Songgu Wu, Junbo Gong*, etc. Agglomeration Mechanism of Azithromycin Dihydrate in Acetone−Water Mixtures and Optimization of the Powder Properties. Industrial and Engineering Chemistry Research. 55(17): 4905-4910 (2016).2019
- 9、 Kangli Li, Junbo Gong*, etc. Oiling out and Polymorphism Control of Pyraclostrobin in Cooling Crystallization. Industrial and Engineering Chemistry Research. 55(44): 11631-11637 (2016) .2019
- 10、 Penglei Cui, Junbo Gong*, etc. Polymorphic Crystallization And Transformation of Candesartan Cilexetil. Industrial and Engineering Chemistry Research. 51(39): 12910–12916 (2012).2019
- 11、 Runyan Li, Junbo Gong*, etc. Correlation of Solubility and Prediction of the Mixing Properties of Ginsenoside Compound K in Various Solvents. Industrial & Engineering Chemistry Research. 51(23): 8141-8148 (2012).2019
- 5、 Yajuan Sun, Junbo Gong*, etc. Template synthesis of PMAA@chitosan hollow nanorods for docetaxel delivery. Polymer Chemistry. 4(8): 2489-2495 (2013).2019
- 4、 Mingyang Chen, Junbo Gong*, etc. Caking and adhesion free energy of maltitol: Studying of mechanism in adhesion process. Powder Technology. 272: 235-240 (2015).2019
- 12、 Bo Yu, Junbo Gong*, etc. Self-template synthesis of core–shell ZnO@ ZIF-8 nanospheres and the photocatalysis under UV irradiation. Materials Letters. 156: 50-53 (2015).2019
- 13、 Liangcheng Song, Junbo Gong*, etc. Measurement and correlation of solubility of clopidogrel hydrogen sulfate (metastable form) in lower alcohols. Journal of Chemical & Engineering Data. 56(5): 2553-2556 (2011).2019
教育经历
- 1995.9-2001.6 Tianjin University Chemical engineering Doctor of Engineering
- 1991.9-1995.6 Tianjin University Technical Economy Bachelor of Management
- 1991.9-1995.6 Tianjin University industrial chemistry Bachelor of Engineering
工作经历
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2016.11 -2019.12
|National institute of crystal science and engineering international joint research center|executive director
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2008.2 -2019.12
|National Engineering Research Center of Industrial Crystallization Technology(NERCICT)|Tianjin University|vice director
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2008.2 -2019.12
|school of chemical engineering|Tianjin University|vice director
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2008.2 -2019.12
|school of chemical engineering|Tianjin university|professor,master's supervisor
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2006.9 -2008.1
|school of pharmacy|University of Michigan|post-doctoral
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2004.7 -2006.9
|school of chemical engineering|Tianjin University|associate professor
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2001.4 -2004.7
|postdoctoral research station|Tianjin teda economic and technological development zone|post-doctoral
专利成果
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Junbo Gong, Shuang Jiang, Baohou Hong, et al. Crystallization method for improving pyraclostrobin bulk density and fluidity (2019)
2020
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Junbo Gong, Cui Huang, Baohou Hong, et al. Method for preparing single crystal fructose (2019)
2020
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Junbo Gong, Songgu Wu, Baohou Hong, et al. Telodisine 1,4. Dioxane solvent compound and preparation method (2019)
2020
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Junbo Gong, Minghe Zhu, Jingkang Wang,, et al.Spherical crystal of sodium chloride and preparation method thereof (2019)
2020
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