The research of Dr. Chen’s group is focused on modern separation and analysis technology applied in pharmacological analysis. The group develops different methods to manufacture superparamagnetic beads and exploits magnetic separation technology in the biomedicine field. Additionally, efforts are extended towards chiral analysis of pharmacological compounds, including the synthesis of novel chiral stationary phases of HPLC, investigating the chiral separation mechanisms through molecular docking and chiral NMR. Our focus is on developing mixed-mode chiral columns that can separate stereoisomeric components with multiple chiral centres simultaneously, thereby improving their quality control.